4-methyl-6,7-dihydro-5H-[1]pyrindine-2-ol
4-Methyl-1,5,6,7-tetrahydro-2H-cyclopenta[b]-pyridin-2-one
CAS: 20594-30-3
Molecular Formula: C9H11NO
4-methyl-6,7-dihydro-5H-[1]pyrindine-2-ol - Names and Identifiers
4-methyl-6,7-dihydro-5H-[1]pyrindine-2-ol - Physico-chemical Properties
| Molecular Formula | C9H11NO |
| Molar Mass | 149.19 |
| Density | 1.13±0.1 g/cm3(Predicted) |
| Melting Point | 243-244 °C(Solv: ethanol (64-17-5)) |
| Boling Point | 378.0±15.0 °C(Predicted) |
| pKa | 13.08±0.40(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD16140309 |
4-methyl-6,7-dihydro-5H-[1]pyrindine-2-ol - Risk and Safety
| Hazard Class | IRRITANT |
4-methyl-6,7-dihydro-5H-[1]pyrindine-2-ol - Introduction
4-Methyl-1,5,6, [B]-pyridin-2-one is an organic compound whose chemical formula is C10H13NO.
Nature:
1. Appearance: 4-Methyl-1,5,6, [B]-pyridin-2-one is white crystal or crystalline powder.
2. Solubility: It can be soluble in a variety of organic solvents, such as methanol, ethanol and acetone, but insoluble in water.
3. melting point: its melting point is about 80-82 ℃.
4. stability: 4-Methyl-1,5,6, [B]-pyridin-2-one is stable under conventional experimental conditions.
Use:
4-Methyl-1,5,6, [B]-pyridin-2 can be used as an intermediate or raw material in organic synthesis. It can be used to synthesize various organic compounds, such as drugs, dyes, pesticides, etc.
Preparation Method:
A common synthetic method is by reacting 2-picolinate with acetone. The specific steps are as follows:
1. In the presence of a base, 2-picolinic acid ester is condensed with acetone to obtain the corresponding condensation product.
2. after acid treatment, the condensation product undergoes a hydrogen transfer reaction to generate 4-Methyl-1,5,6, [B]-pyridin-2-one.
3. Finally, the pure product is obtained by crystal chemistry method or coagulation reaction.
Safety Information:
although specific safety information needs to refer to relevant literature or safety data sheets provided by manufacturers, in general, 4-Methyl-1,5,6, [B]-pyridin-2-one has no obvious toxicity and danger under general experimental conditions. However, the following should be noted during use:
1. should wear protective glasses and gloves, avoid contact with the skin and inhalation of dust.
2. Avoid dust during operation to prevent irritation caused by inhalation or contact.
3. Because it is an organic compound, it should be operated in a well-ventilated place.
4. When disposing of waste liquids and wastes, they should be disposed of in accordance with local environmental regulations.
When using this compound, it is recommended to refer to the relevant safety data sheet and operating procedures to ensure correct and safe operation.
Nature:
1. Appearance: 4-Methyl-1,5,6, [B]-pyridin-2-one is white crystal or crystalline powder.
2. Solubility: It can be soluble in a variety of organic solvents, such as methanol, ethanol and acetone, but insoluble in water.
3. melting point: its melting point is about 80-82 ℃.
4. stability: 4-Methyl-1,5,6, [B]-pyridin-2-one is stable under conventional experimental conditions.
Use:
4-Methyl-1,5,6, [B]-pyridin-2 can be used as an intermediate or raw material in organic synthesis. It can be used to synthesize various organic compounds, such as drugs, dyes, pesticides, etc.
Preparation Method:
A common synthetic method is by reacting 2-picolinate with acetone. The specific steps are as follows:
1. In the presence of a base, 2-picolinic acid ester is condensed with acetone to obtain the corresponding condensation product.
2. after acid treatment, the condensation product undergoes a hydrogen transfer reaction to generate 4-Methyl-1,5,6, [B]-pyridin-2-one.
3. Finally, the pure product is obtained by crystal chemistry method or coagulation reaction.
Safety Information:
although specific safety information needs to refer to relevant literature or safety data sheets provided by manufacturers, in general, 4-Methyl-1,5,6, [B]-pyridin-2-one has no obvious toxicity and danger under general experimental conditions. However, the following should be noted during use:
1. should wear protective glasses and gloves, avoid contact with the skin and inhalation of dust.
2. Avoid dust during operation to prevent irritation caused by inhalation or contact.
3. Because it is an organic compound, it should be operated in a well-ventilated place.
4. When disposing of waste liquids and wastes, they should be disposed of in accordance with local environmental regulations.
When using this compound, it is recommended to refer to the relevant safety data sheet and operating procedures to ensure correct and safe operation.
Last Update：2024-04-09 21:00:56
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